The confirmation of Trump's new crown is a global sensation . But he is not the first national leader to confirm the new crown .
According to ABC , Afternoon est 6 spot 15 branch , Trump, who confirmed the new crown, has put on a mask and walked out of the White House , Towards his royal vehicle, marine one （Marine
One）. period , He waved to the crowd occasionally , But did not stop to accept any reporter's questions .
According to NBC financial channel （CNBC） report , local time 10 month 2 day , Former U.S. Food and Drug Administration （FDA） Director Scott Gottlieb
The doctor said in an interview , He thinks the White House is deciding to use it for trump Regeneron（ Regenerant ） Pharmaceutical company's experimental new coronavirus antibody cocktail therapy before , All treatments must have been carefully considered .
Gottlieb stay CNBC Of 《Fast Money》 It's said in the program ,“ Giving trump active treatment is a perfectly appropriate decision , Then there is the question of which treatment to choose .”
Second from the left ：Scott Gottlieb
Since trump was diagnosed , White House “ Out of great caution ” Send it to Walter Reed National Military Medical Center .
Trump arrives at Walter Reed National Military Medical Center
Gottlieb Added ：“ I won't choose between them Regeneron Nothing can be inferred from the fact that the products of other pharmaceutical companies are not . As far as they know ,Regeneron
The antibody cocktail seems to be the most effective product .”
however , Not everyone in the medical world is like that Gottlieb
The decision to give trump an experimental treatment was also agreed . Some people offer this to the president “ Special treatment ” Expressing concern , Because the drug has not yet been approved by federal regulators ; Others point to the limited data available for the product .
Just like a doctor in Twitter It's like the comment ：“ no data ,VIP Drugs don't mean better drugs .”
The White House did not immediately respond CNBC Comments on the decision to inject trump with antibody drugs .
Regeneron confirm , It has been provided to trump 8 Gram dose REGN-COV2 Therapeutic drugs . The drug is still in the experimental stage , Not yet available FDA
Emergency use authorization for , But it provides a sympathetic response to the use request .
according to CNBC report , In connection with Regeneron Chief scientific officer George Yancopoulos
After talking to the doctor, I learned that ,“ A limited number of patients ” The drug was also accepted on this basis .
REGN-COV2 It's two monoclonal antibodies （REGN10933 and
REGN10987） The combination of , Designed to block novel coronavirus that causes novel coronavirus pneumonia . It simulates the human body's response to foreign invaders . Its purpose is to enhance the defense ability of the immune system , Instead of waiting for the human biological process to complete its work .
These antibodies come from genetically modified mice with a human immune system , And antibodies identified from novel coronavirus pneumonia rehabilitative patients . Two effective virus neutralizing antibodies were formed REGN-COV2. according to
Regeneron call , The antibody cocktail is associated with the spike protein of new coronavirus （S protein ） There is no competitive binding between the key receptor binding domains of , It reduces the ability of the mutant virus to evade treatment , So as to protect the human body from mutation S
protein . Preclinical studies have shown that ,REGN-COV2 It can reduce viral load and associated damage in non-human primates .
local time 9 month 29 day ,Regeneron Said on its website , their REGN-COV2
Treatment improved symptoms and novel coronavirus pneumonia in hospitalized patients with mild to moderate pneumonia . This is based on the previous 275 Data of trial patients . The company said at the time , Planning and inclusion FDA
Internal regulators “ rapid ” Discuss early results .
stay Regeneron initial 275 Average age 44 Among the participants, the age of ,49% Of the participants were men ,51% It's a woman ; about 56% It's Hispanic ,13%
It's African American ,64% Novel coronavirus pneumonia is a potential risk factor for one or more severe new crown pneumonia. , Including obesity （ exceed 40%）.
in addition ,Regeneron It's not the only company to develop antibody drugs , Lilly and GlaxoSmithKline are also testing monoclonal antibodies , Experts believe this is novel coronavirus pneumonia treatment .
In a memo provided by the White House on Friday , Trump's doctor Sean Conley say ：“ As a precaution , The president accepted Regeneron Antibody cocktail therapy .”Conley
He also wrote , Trump is still tired , But the mood is good .
A person familiar with the matter said , Trump has had a fever since Friday morning .
in addition , According to the news agency , Trump's aides began to feel him on Wednesday “ Feeling unwell ”,“ Seems exhausted ”, But he thinks it has something to do with his busy campaign schedule .
《 New York Times 》 The same report said , Trump seemed to be at a fundraising event on Thursday “ be in the blues ”, It's said to have returned from the rally on Wednesday , He was still asleep on his plane .
Gottlieb express , If Trump is to novel coronavirus pneumonia, he will be treated early. , Probably the first thing that comes to mind is Gilead science remdesivir（ Remdesivir ）. Because it has been acquired FDA
Emergency use authorization for , But it only applies to critically ill inpatients .
Gottlieb say ：“ I thought they were going to use radsey , Because there's a lot of data on this drug .” He added , He was right Regeneron
The therapeutic effect of “ optimistic ” attitude , But it may be too early .
however , For trump to accept Regeneron The saying that treatment should arouse vigilance ,Gottlieb
Refuted . He said , Almost all other Americans , When they diagnosed the novel coronavirus pneumonia , They will be monitored by medical professionals , I hope the symptoms don't get worse .
say ：“ For the president of the United States , If you have a treatment available , I think you will provide treatment , Especially if you know the safety of these products , And you believe it's safe , It won't make his condition worse .”
however , Some doctors are skeptical about the decision to treat trump with antibody drugs .
Assistant professor of medicine and licensed hematooncologist at the University of California, San Francisco Vinay Prasad The doctor is here Twitter
It says ：“ Handing over unproven things to powerful people , It's bad science and bad medical ethics .”
Chest specialist in Seattle Vin Gupta
The doctor added ：“ I want to say , I've never heard of a patient , Especially important people like the president , He received an experimental antibody cocktail therapy .” He also called on the White House to provide more information .
except Regeneron Antibody cocktail therapy , Trump also took zinc , vitamin D And famotidine （ histamine H_2 Receptor blockers ）.
Gottlieb say , Famotidine treatment is still only “ Speculative ” Of , Although researchers are studying novel corontin in patients with novel coronavirus pneumonia . He added ：“ Studies have shown that , If you lack vitamins
D, Vitamin supplement D It's good , But you'd better supplement it before you get sick . I don't think there's anything wrong with these drugs or they could cause harm , I just don't know if they will provide a therapeutic effect in this case .”
in addition , CATV News Network （CNN） Trump's focus on novel coronavirus pneumonia is the focus .
Trump already has several risk factors , It belongs to high risk group . The details are as follows ：
Age ： According to the Centers for Disease Control and prevention （CDC） Data for , And 18-29 Compared with young people ,65-74 The risk of hospitalization is higher in the age group 5 times , The risk of novel coronavirus pneumonia is higher.
90 times .
Obesity ： According to him 4 Monthly physical examination report , Trump weight 244（ about 111 Kg ） pound , height 6 foot 3 inch （ about 191cm）. This brings his body mass index to
30.5. In theory , If it's mild obesity , according to CDC Data for , Obesity has increased the novel coronavirus pneumonia risk by two times .
Male ： Trump is a man . According to authoritative health agencies , The novel coronavirus pneumonia is more likely for men to die or suffer from severe new crown pneumonia .
other ： I don't know if trump has any other diseases that might put him in a high-risk group . According to his recent physical examination , His blood pressure is only slightly elevated . There is no evidence that he has cancer , nephropathy , Diabetes or other diseases that put people at higher risk .